CD81 Monoclonal Antibody (1D6)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA181488 | 500 µg | 982,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This product is a low-endotoxin, preservative-free formulation. Endotoxin level is <0.01 EU/ug. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. Mouse anti Human CD81 antibody, clone 1D6 recognizes human CD81, a 26 kDa cell surface antigen also known as TAPA-1, and a member of the tetraspanin family. CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T cells. In muscles, CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. Like members of the tetraspanin family that include CD9, CD37, CD53, CD63, and CD82, CD81 is a cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that is known to complex with integrins.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, ICC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | OCI-LY8 cells aggregated by 5A6 (another CD81 antibody). |
Host | Ms |
Clone Number | [1D6] |
Genebank | CD81 |
Isotype | IgG1 |
Crossreactivity | Chimpanzee, Gt, Hu, Sh |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with no preservative |
Concentration | 1 mg/mL |
Working Dilution | Immunoprecipitation (Assay-dependent), Functional Assay (Assay-dependent), Flow Cytometry (1/10),... |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA1-81488 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |