P-Selectin Monoclonal Antibody (Psel.KO.2.7), PE
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA181849 | 100 Tests | 630,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. Mouse anti human CD62P, clone Psel.KO.2.7, recognizes human P-Selectin. P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. From there, it can be rapidly brought to the cell surface after exposure to thrombin, histamine, complement 5a, Ca21 ionophores, or adenosine diphosphate. P-selectin protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. P-selectin plays an important role in adhesive processes between leucocytes and endothelial cells, and is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens found on neutrophils and monocytes. P-selectin is constitutively expressed in inflammation and contributes to atherogenesis, throm
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | P-selectin transfected 300.19 cells. |
Host | Ms |
Clone Number | [Psel.KO.2.7] |
Genebank | SELP |
Isotype | IgG1 |
Crossreactivity | Bo, Ho, Ca, Gt, Hu, Ms, Sh, Rt |
Clonality | Mab |
Format | Lyophilized; PBS; pH 7.4, with 1% BSA, 5% sucrose and 0.09% sodium azide |
Working Dilution | Flow Cytometry (Neat-1:5) |
Purity | Protein A |
Conjugation | PE |
Storage Conditions | 4° C, store in dark, DO NOT FREEZE! |
Disclaimer | Alternative CatNo: MA1-81849 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |