AP2 alpha Monoclonal Antibody (3B5)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA1872 | 100 µL | 648,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA1-872 detects AP-2 from human, mouse, and chicken samples. MA1-872 has been successfully used in Western blot, immunoprecipitation, and immunofluorescence applications. By Western blot, this antibody detects a 45-50 kDa band representing AP-2. For Western blotting, block with BSA only (not milk). The MA1-872 immunogen is the N-terminus of human AP2a. TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
Category | Antibody |
Supplier | ThermoFisher |
Application | ICC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | N-terminus of human AP2a. |
Host | Ms |
Clone Number | [3B5] |
Genebank | TFAP2A |
Isotype | IgG2b |
Crossreactivity | Ck, Hu, Ms |
Clonality | Mab |
Format | Liquid; PBS; , with 1mg/mL BSA and 0.05% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Western Blot (1:50 - 1:200), Immunoprecipitation (1:100 - 1:250), Immunocytochemistry (1:50-1:500... |
Purity | Protein G |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA1-872 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |