Endothelin 1 Monoclonal Antibody (TR.ET.48.5)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA3005 | 100 µL | 618,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA3-005 detects ET-1 from human, sheep, mouse and rat tissues. This antibody shows little cross-reactivity to related peptides and no known cross-reactivity to non-related peptides. MA3-005 has been successfully used in Western blot, flow cytometry, immunofluorescence, immunohistochemistry, immunocytochemistry, and radioimmune assay procedures. Immunohistochemical staining of ET-1 in human corpus cavernosum tissue with MA3-005 results in staining of endothelial cells. Radioimmune assays using MA3-005 can be used to concentrate ET-1 in solution (e.g. serµm/plasma, milk, urine). This antibody is not recommended for human placenta tissue or HepG2 cells in Western blot applications. For immunohistochemistry with MA3-005 formalin-fixed, paraffin-embedded tissue sections has been used. The MA3-005 antigen is purified human endothelin-1. Studies suggest that this antibody binds to an epitope in the region of ET-1 represented by amino acids 8-16. The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been foun
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, ICC, IHC, RIA, WB |
Regulatory Status | RUO |
Immunogen | Pure endothelin-1 conjugated to KLH. |
Host | Ms |
Clone Number | [TR.ET.48.5] |
Genebank | EDN1 |
Isotype | IgG1 |
Crossreactivity | Hu, Ms, Sh, Rt |
Clonality | Mab |
Format | Liquid; PBS; , with 0.05% sodium azide |
Concentration | 2.5 mg/mL |
Working Dilution | Immunohistochemistry (Paraffin) (1:250), Immunohistochemistry (Frozen) (1:250), Immunocytochemist... |
Purity | Affinity chromatography |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA3-005 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |