ATP4B Monoclonal Antibody (2G11)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA3923 | 100 µL | 632,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA3-923 detects the beta-subunit of hydrogen/potassium ATPase from bovine, human, canine, porcine, rabbit, mouse, ferret, and rat tissues. MA3-923 has been successfully used in Western blot, immunohistochemistry, immunocytochemistry, and immunoprecipitation procedures (ChIP). By Western blot, this antibody detects various forms of the beta-subunit, including a 60 to 80 kDa glycosylated protein, a 52 kDa beta-subunit precursor, and the 34 kDa core peptide from rabbit stomach extracts. Immunohistochemical staining of hydrogen/potassium ATPase in rabbit gastric glands with MA3-923 results in specific staining of parietal cells. MA3-923 has been shown to inhibit the enzymatic activity of the hydrogen/potassium ATPase and to alter the affinity of the cytoplasmic potassium binding site. The MA3-923 antigen is purified 34 kDa core peptide from deglycosylated hog gastric microsomes. This antibody recognizes an epitope between amino acid residues 1-13 or 15-28 located on the cytoplasmic side of the beta-subunit. The hydrogen/potassium ATPase, or gastric proton pump, belongs to a family of P-type cation-transporting ATPases. This family of ATPases shares a number of functional and structural similarities including the common feature of consisting of an alpha and beta subun
Category | Antibody |
Supplier | ThermoFisher |
Application | ChIP, FC, ICC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | Purified 34 kDa core peptide from deglycosylated hog gastric microsomes. |
Host | Ms |
Clone Number | [2G11] |
Genebank | ATP4B |
Isotype | IgG1 |
Crossreactivity | Bo, Dg, Hu, Ms, Mustelid, Pg, Rb, Rt |
Clonality | Mab |
Format | Liquid; ascites; diluted in PBS, with 0.05% sodium azide |
Working Dilution | Flow Cytometry (1/50), Western Blot (1:4,000), ChIP Assay (Assay-dependent), Immunocytochemistry ... |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA3-923 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |