Cytochrome C Monoclonal Antibody (CTC03 (2B5))
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA511823 | 500 µL | 678,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA5-11823 targets Cytochrome c in ELISA, FACS, immunofluorescence and immunoprecipitation applications and shows reactivity with Bovine, Canine, Equine, Mouse and Human samples. MA5-11823 is not suitable for Western blotting applications. This antibody was orginally validated as part of a Thermo Scientific Cellomics High Content Screening Kit. The antibody sold separately may have slightly different performance and may need to be further optimized for the best results. Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, FC, ICC, IP |
Regulatory Status | RUO |
Immunogen | Equine cytochrome c |
Host | Ms |
Clone Number | [CTC03 (2B5)] |
Genebank | CYCS |
Isotype | IgG2a,k |
Crossreactivity | Bo, Dg, Ho, Hu, Ms |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 0.2% BSA and 0.09% sodium azide |
Concentration | 0.2 mg/mL |
Working Dilution | ELISA (Assay-dependent), Flow Cytometry (Assay-dependent), Immunoprecipitation (2 µg/mL), Immunoc... |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: MA5-11823 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |