GRB2 Monoclonal Antibody (2GB04 (C1.4))
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA512165 | 500 µL | 518,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA5-12165 targets Grb2 in IF and IHC (P) applications and shows reactivity with Bovine, Human, mouse, Rat, and Xenopus laevis samples. The MA5-12165 immunogen is purified recombinant human Grb2 protein. GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC |
| Regulatory Status | RUO |
| Immunogen | Purified recombinant human Grb2 protein |
| Host | Ms |
| Clone Number | [2GB04 (C1.4)] |
| Genebank | GRB2 |
| Isotype | IgG1,k |
| Crossreactivity | Bo, Hu, Ms, Rt, Xenopus |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.2% BSA and 0.09% sodium azide |
| Concentration | 0.2 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (1-2 µg/mL) |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | 4° C |
| Disclaimer | Alternative CatNo: MA5-12165 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
