Prohibitin Monoclonal Antibody (II-14-10)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA512858 | 500 µL | 758,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA5-12858 targets Prohibitin in immunofluorescence, immunohistochemistry (paraffin), and Western blot applications and shows reactivity with Chicken, Human, mouse, Porcine, and Rat samples. The MA5-12858 immunogen is purified recombinant rat prohibitin protein. Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Purified recombinant rat prohibitin protein |
| Host | Ms |
| Clone Number | [II-14-10] |
| Genebank | PHB |
| Isotype | IgG1 |
| Crossreactivity | Ck, Hu, Ms, Primate, Pg, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.2% BSA and 0.09% sodium azide |
| Concentration | 0.2 mg/mL |
| Working Dilution | Western Blot (0.5-1.0 µg/mL), Immunohistochemistry (Paraffin) (2-4 µg/mL) |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Cold Room (2 to 8 C) |
| Disclaimer | Alternative CatNo: MA5-12858 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
