Transferrin Monoclonal Antibody (F2H8G6)

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Product Description

MA5-14690 has been successfully used in ELISA, immunofluorescence, and immunoprecipitation, and radioimmune assay applications, and reacts with human samples. MA5-14690 detects Transferrin which has a predicted molecular weight of approximately 67 kDa. Product MA514690 is a smaller package size of MIT0603 (formerly sold as a Seradyn product). Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.