Histone H2B Monoclonal Antibody (C.362.2)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA514835 | 100 µL | 604,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other histones. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide corresponding to the carboxy-terminal residues of histone H2B |
| Host | Ms |
| Clone Number | [C.362.2] |
| Genebank | H2B |
| Isotype | IgG1 |
| Crossreactivity | Hu, Ms, Primate, Rt, Zebrafish |
| Clonality | Mab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and <0.02% sodium azide |
| Concentration | 12 mg/mL |
| Working Dilution | Western Blot (1:1,000), ChIP Assay (1.5 µg/1x10^6 cells) |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Disclaimer | Alternative CatNo: MA5-14835 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
