AKT Pan Monoclonal Antibody (J.314.4)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA514916 | 100 µL | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other related proteins. AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide corresponding to residues in the carboxy-terminal sequence of mouse Akt |
| Host | Rb |
| Clone Number | [J.314.4] |
| Genebank | AKT1 |
| Isotype | IgG |
| Crossreactivity | Drosophila, Hu, Ms, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and <0.02% sodium azide |
| Concentration | 35 µg/mL |
| Working Dilution | Immunocytochemistry (1:200-800), Immunohistochemistry (Paraffin) (1:150-600), Immunoprecipitation... |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Disclaimer | Alternative CatNo: MA5-14916 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
