Ku80 Monoclonal Antibody (S.669.4)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA514953 | 100 µL | 656,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic peptide corresponding to the carboxy terminus of human Ku80 |
| Host | Rb |
| Clone Number | [S.669.4] |
| Genebank | XRCC5 |
| Isotype | IgG |
| Crossreactivity | Hu, Primate |
| Clonality | Mab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and <0.02% sodium azide |
| Concentration | 7.1 µg/mL |
| Working Dilution | Immunocytochemistry (1:200-1:400), Immunohistochemistry (Frozen) (1:800), Immunohistochemistry (P... |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-14953 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
