GEF-H1 Monoclonal Antibody (K.607.1)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA515027 | 100 µL | 684,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic peptide corresponding to the sequence of human GEF-H1 |
| Host | Rb |
| Clone Number | [K.607.1] |
| Genebank | ARHGEF2 |
| Isotype | IgG |
| Crossreactivity | Hm, Hu, Ms, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and <0.02% sodium azide |
| Working Dilution | Western Blot (1:1,000), Immunoprecipitation (1:50) |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-15027 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
