PARP1 Monoclonal Antibody (C.384.8)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA515031 | 100 µL | 686,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with PARP-2 and PARP-3. Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic peptide corresponding to residues surrounding Gly623 of human PARP-1 |
| Host | Rb |
| Clone Number | [C.384.8] |
| Genebank | PARP1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and <0.02% sodium azide |
| Concentration | 438 µg/mL |
| Working Dilution | Immunocytochemistry (1:800), Immunoprecipitation (1:200), Western Blot (1:500), ChIP Assay (4 µL/... |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-15031 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
