Phospho-MEK1/MEK2 (Ser221) Monoclonal Antibody (K.742.1)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA515118 | 100 µL | 686,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. MEK 1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In brain, this pathway also plays a key role in synaptic (Adams and Sweatt, 2002). Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer221 of human MEK1/2 |
| Host | Rb |
| Clone Number | [K.742.1] |
| Genebank | MAP2K1 |
| Isotype | IgG |
| Crossreactivity | Dg, Hu, Ms, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and <0.02% sodium azide |
| Concentration | 246 µg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (1:50), Flow Cytometry (1:100), Western Blot (1:2,000) |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-15118 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
