Histone H3 Monoclonal Antibody (E.960.2)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA515150 | 100 µL | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other core histones. Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide corresponding to the carboxy-terminal residues of human histone H3 |
| Host | Rb |
| Clone Number | [E.960.2] |
| Genebank | H3C1 |
| Isotype | IgG |
| Crossreactivity | Bo, Dg, Drosophila, Hm, Hu, Ms, Primate, Pg, Rt, Zebrafish |
| Clonality | Mab |
| Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and <0.02% sodium azide |
| Concentration | 21 µg/mL |
| Working Dilution | Western Blot (1:1,000) |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Disclaimer | Alternative CatNo: MA5-15150 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
