Phospho-JNK1/JNK2 (Thr183, Tyr185) Monoclonal Antibody (E.665.10)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA515228 | 200 µL | 600,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Antibodies to this protein (and modification) were previously sold as part of a Thermo Scientific Cellomics High Content Screening Kit. This replacement antibody is now recommended for researchers who need an antibody for high content cell based assays. It has been thoroughly tested and validated for cellular immunofluorescence (IF) applications. Further optimization including the selection of the most appropriate fluorescent Dylight conjugated secondary antibody may have to be performed for your high content assay. It is not recommended to aliquot this antibody. C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
Category | Antibody |
Supplier | ThermoFisher |
Application | ChIP, FC, ICC, IP, WB |
Regulatory Status | RUO |
Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pThr183/Tyr185 of human SAPK/JNK |
Host | Ms |
Clone Number | [E.665.10] |
Genebank | MAPK8 |
Isotype | IgG1 |
Crossreactivity | Hm, Hu, Ms, Rt, Yeast |
Clonality | Mab |
Format | Liquid; 0.01M HEPES; pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol and <0.02% sodium azide |
Concentration | 771 µg/mL |
Working Dilution | Flow Cytometry (1:400), Immunocytochemistry (1:200), Immunoprecipitation (1:250), Western Blot (1... |
Purity | Affinity chromatography |
Conjugation | Unconjugated |
Storage Conditions | -20°C |
Disclaimer | Alternative CatNo: MA5-15228 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |