HDAC3 Monoclonal Antibody (7G6C5)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA515442 | 100 µL | 758,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA5-15442 targets HDAC3 in IF, ChIP and WB applications and shows reactivity with Human samples. The MA5-15442 immunogen is purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli. MA5-15442 detects HDAC3 which has a predicted molecular weight of approximately 48.8kDa. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, EL, ICC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli. |
| Host | Ms |
| Clone Number | [7G6C5] |
| Genebank | HDAC3 |
| Isotype | IgG2a |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Liquid; ascites; , with 0.03% sodium azide |
| Working Dilution | ELISA (1:10,000), ChIP Assay (4 µl/10^6 cells), Western Blot (1:500-1:2,000), Immunocytochemistry... |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-15442 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
