GSK3B Monoclonal Antibody (3D10)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA515597 | 100 µL | 762,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA5-15597 targets GSK3B in FACS, IF, IHC, and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples. The MA5-15597 immunogen is purified recombinant fragment of human GSK3B expressed in E. Coli.
. MA5-15597 detects GSK3B which has a predicted molecular weight of approximately 46kDa. GSK3B is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, FC, ICC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Purified recombinant fragment of human GSK3B expressed in E. Coli. |
| Host | Ms |
| Clone Number | [3D10] |
| Genebank | GSK3B |
| Isotype | IgG2a |
| Crossreactivity | Hu, Ms, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; ascites; , with 0.03% sodium azide |
| Working Dilution | Flow Cytometry (1:200 - 1:400), Western Blot (1:500), Immunocytochemistry (1:200-1:1,000), ELISA ... |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-15597 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
