Blimp-1 Monoclonal Antibody (3H2-E8), DyLight™ 550
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA516117 | 100 µL | 662,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In Western Blot, this antibody recognizes a band at ~98 kDa and may recognize one at ~80 kDa (the beta form). Antigen retrieval is recommended (EDTA buffer, microwave) prior to IHC on paraffin tissues. This antibody does not immunoprecipitate.For IHC and ICC/IF a dilution of 1:200 is recommended with tyramide amplification; this antibody demonstrates nuclear staining. Suggested positive control: P3X (murine plasmocytoma) cell lysates. Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus. It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells. It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, FC, ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | A fragment of the mouse Blimp-1 (residues 199-409). |
| Host | Ms |
| Clone Number | [3H2-E8] |
| Genebank | PRDM1 |
| Isotype | IgG1 |
| Crossreactivity | Hu, Ms, Pg |
| Clonality | Mab |
| Format | Liquid; 50mM sodium borate; , with 0.05% sodium azide |
| Concentration | 0.69 mg/mL |
| Working Dilution | ELISA (1:100-1:2,000), Flow Cytometry (8 µg/mL), Immunocytochemistry (1:50-1:200), Immunohistoche... |
| Purity | Protein G |
| Conjugation | DY 550 |
| Storage Conditions | 4° C, store in dark |
| Disclaimer | Alternative CatNo: MA5-16117 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
