TLR8 Monoclonal Antibody (44C143)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA516190 | 100 µg | 630,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | DB, FC, ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | KLH-conjugated synthetic peptide of human TLR8, within amino acids 750-850. It will cross-react with mouse TLR8. |
| Host | Ms |
| Clone Number | [44C143] |
| Genebank | TLR8 |
| Isotype | IgG1,k |
| Crossreactivity | Hu, Ms, Rb |
| Clonality | Mab |
| Format | Liquid; PBS; , with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Flow Cytometry (0.5-1 µg per million cells), Immunohistochemistry (Paraffin) (5 µg/mL), Western B... |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA5-16190 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
