AGR2 Monoclonal Antibody (10E2)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA516244 | 100 µg | 686,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A portion of amino acids 50-100 of human AGR2 was used as the immunogen for the antibody. |
| Host | Ms |
| Clone Number | [10E2] |
| Genebank | AGR2 |
| Isotype | IgG1,k |
| Crossreactivity | Bo, Dg, Ho, Hu, Ms, Primate, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; , with 0.05% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Western Blot (4-6 µg/mL), Immunohistochemistry (Paraffin) (5 µg/mL) |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-16244 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
