Factor VIII Monoclonal Antibody (RFF-VIIIC/8)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA516933 | 500 µg | 754,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody does not react with dog, mouse or rat. Mouse anti Human Factor VIII antibody, clone RFF-VIIIC/8 recognizes human Factor VIII, an essential blood coagulation factor. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, RIA, WB |
Regulatory Status | RUO |
Immunogen | Affinity purified human Factor VIII |
Host | Ms |
Clone Number | [RFF-VIIIC/8] |
Genebank | F8 |
Isotype | IgG1 |
Crossreactivity | Hu, Pg |
Clonality | Mab |
Format | Liquid; PBS; , with 0.09% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | ELISA (1:500-1:15,000), Radioimmune assays (Assay-dependent), Western Blot (Assay-dependent) |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | 4°C or -20°C if preferred |
Disclaimer | Alternative CatNo: MA5-16933 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |