RUNX3 Monoclonal Antibody (2B3)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA517169 | 100 µg | 598,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MA5-17169 targets RUNX3 in FACS, ICC, IHC, IF and WB applications and shows reactivity with Human and Mouse samples. The MA5-17169 immunogen is purified recombinant fragment of human RUNX3 (amino acids:186-252) expressed in E. Coli. MA5-17169 detects RUNX3 which has a predicted molecular weight of approximately 44.4kDa. This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, EL, FC, ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Purified recombinant fragment of human RUNX3 (amino acids:186-252) expressed in E. Coli. |
| Host | Ms |
| Clone Number | [2B3] |
| Genebank | RUNX3 |
| Isotype | IgG2b |
| Crossreactivity | Hu, Ms |
| Clonality | Mab |
| Format | Liquid; PBS; , with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Flow Cytometry (1:200 - 1:400), Immunocytochemistry (1:200-1:1,000), Western Blot (1:500-1:2,000)... |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA5-17169 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
