LAMP2 Monoclonal Antibody (M3/84)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA517861 | 100 µg | 348,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
LAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is approximately 46 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of about 100-130 kDa. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail. LAMP2 is used to monitor a very selective form of autophagy called chaperone-mediated autophagy. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail. The LAMP protein has 3 variant forms: LAMP-2A, -2B, and 2C. LAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful
Category | Antibody |
Supplier | ThermoFisher |
Application | Ctox, FC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | Immunoadsorbent purified mouse macrophage glycoprotein fraction. |
Host | Rt |
Clone Number | [M3/84] |
Genebank | LAMP2 |
Isotype | IgG1,k |
Crossreactivity | Ms |
Clonality | Mab |
Format | Liquid; PBS; , with 0.02% sodium azide |
Concentration | 1 mg/mL |
Working Dilution | Flow Cytometry (1.0 µg/1x10^6 cells), Immunohistochemistry (Frozen) (Assay-dependent), Cytotoxici... |
Purity | Protein G |
Conjugation | Unconjugated |
Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Disclaimer | Alternative CatNo: MA5-17861 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |