HDAC1 Monoclonal Antibody (10E2)


Catalog Number Pack Size List Price* Quantity
MA518071 100 µL 838,00 Add

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Product Description

This target has a predicted molecular weight of 55 kDa. Actual Western blot results show a band at 57 kDa. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.

Category Antibody
Supplier ThermoFisher
Application ChIP, FC, ICC, IHC, IP, WB
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen Synthetic peptide: EEKPEAKGVKEEVKLA, corresponding to C terminal amino acids 467-482 of Human and mouse HDAC1
Host Ms
Clone Number [10E2]
Genebank HDAC1
Isotype IgG1
Crossreactivity Hu, Ms, Rt
Clonality Mab
Format Liquid; PBS; , with 0.1% sodium azide
Concentration 1 mg/mL
Working Dilution Immunocytochemistry (1 µg/mL), Immunohistochemistry (Paraffin) (Assay-dependent), Immunoprecipita...
Purity Protein G
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: MA5-18071
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Ambient
Material Safety Data Sheet Download PDF