MCP-1 Monoclonal Antibody (23007)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA523712 | 500 µg | 602,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In ELISAs, this antibody does not cross-react with recombinant mouse (rm) CCL2, 3, 4, rhCCL3, 4, 5, 7, or 8. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method. This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, IHC, N, WB |
| Regulatory Status | RUO |
| Immunogen | E. coli-derived recombinant human CCL2/JE/MCP-1 |
| Host | Ms |
| Clone Number | [23007] |
| Genebank | CCL2 |
| Isotype | IgG2b |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Lyophilized; PBS; , with 5% trehalose and No Preservative |
| Concentration | 0.5 mg/mL |
| Working Dilution | ELISA (0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture)), Neutralization (0.5-2.0 µg/mL), Western B... |
| Purity | Protein A/G |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: MA5-23712 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
