CNTF Monoclonal Antibody (34738)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA523730 | 500 µg | 580,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In sandwich ELISAs, less than 3% cross-reactivity with recombinant human CNTF is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <1.0 EU per 1 µg of the antibody by the LAL method. The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, N |
Regulatory Status | RUO |
Immunogen | E. coli-derived recombinant rat CNTF Ala2-Met200 |
Host | Ms |
Clone Number | [34738] |
Genebank | CNTF |
Isotype | IgG2b |
Crossreactivity | Rt |
Clonality | Mab |
Format | Lyophilized; PBS; , with 5% trehalose and No Preservative |
Concentration | 0.5 mg/mL |
Working Dilution | ELISA (0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture)), Neutralization (1-3 µg/mL) |
Purity | Protein A/G |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA5-23730 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |