IL-13 Monoclonal Antibody (38213)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA523735 | 500 µg | 656,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In ELISAs, this antibody shows less than 0.1% cross-reactivity with recombinant human IL-13. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, N, WB |
Regulatory Status | RUO |
Immunogen | E. coli-derived recombinant mouse IL-13 |
Host | Rt |
Clone Number | [38213] |
Genebank | IL13 |
Isotype | IgG2a |
Crossreactivity | Ms |
Clonality | Mab |
Format | Lyophilized; PBS; , with 5% trehalose and No Preservative |
Concentration | 0.5 mg/mL |
Working Dilution | ELISA (0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture)), Neutralization (0.3-0.8 µg/mL), Western B... |
Purity | Protein A/G |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA5-23735 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |