IL-19 Monoclonal Antibody (152112)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA523778 | 500 µg | 592,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method. The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, N |
| Regulatory Status | RUO |
| Immunogen | E. coli-derived recombinant human IL-19 Leu25-Ala177 |
| Host | Ms |
| Clone Number | [152112] |
| Genebank | IL19 |
| Isotype | IgG2b |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Lyophilized; PBS; , with 5% trehalose and No Preservative |
| Concentration | 0.5 mg/mL |
| Working Dilution | Flow Cytometry (2.5 µg per million cells), Neutralization (0.2-0.5 µg/mL) |
| Purity | Protein A/G |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: MA5-23778 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
