BMP-7 Monoclonal Antibody (164311)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA523877 | 100 µg | 602,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) BMP-6 is observed and no cross-reactivity with rhBMP-2, -3, -4, -5, or -8 is observed. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC, N, WB |
| Regulatory Status | RUO |
| Immunogen | CHO-derived recombinant human BMP-7 Ser293-His431 |
| Host | Ms |
| Clone Number | [164311] |
| Genebank | BMP7 |
| Isotype | IgG2b |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Liquid; PBS; , with 5% trehalose and No Preservative |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (8-25 µg/mL), Neutralization (1.5-6.0 µg/mL), Western Blot (1 µg/mL) |
| Purity | Protein A/G |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: MA5-23877 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
