IL2RG Monoclonal Antibody (633162)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA524286 | 100 µg | 564,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha, rhIL-2 R beta, rhIL-15 R alpha, recombinant mouse IL-2 R gamma, or recombinant canine IL-2 R alpha is observed. In Western blots, approximately 80% cross-reactivity with recombinant human IL-2 R beta, 50% cross-reactivity with rhIL-15 R alpha and recombinant mouse IL-2 R alpha, and no cross-reactivity with rhIL-2 R alpha is observed. Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method. IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, N |
Regulatory Status | RUO |
Immunogen | Sf 21-derived recombinant human Common gamma Chain/IL-2 gamma Leu23-Asn254 |
Host | Ms |
Clone Number | [633162] |
Genebank | IL2RG |
Isotype | IgG2b |
Crossreactivity | Hu |
Clonality | Mab |
Format | Lyophilized; PBS; , with 5% trehalose and No Preservative |
Concentration | 0.5 mg/mL |
Working Dilution | Flow Cytometry (2.5 µg per million cells), Neutralization (0.08-0.4 µg/mL) |
Purity | Protein A/G |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA5-24286 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |