Fumarase Monoclonal Antibody (GT7612)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA527746 | 100 µL | 656,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Positive Control: 293T, A431, HeLa, HepG2, mouse liver, rat liver Predicted Reactivity: Zebrafish (90%), Pig (98%), Chicken (91%), Sheep (99%), Chimpanzee (99%), Bovine (98%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Fumarate hydratase. The exact sequence is proprietary. |
| Host | Ms |
| Clone Number | [GT7612] |
| Genebank | FH |
| Isotype | IgG3 |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; , with no preservative |
| Concentration | 3 mg/mL |
| Working Dilution | Western Blot (1:500-1:3,000), Immunocytochemistry (1:100-1:1,000) |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA5-27746 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
