GAPDH Recombinant Rabbit Monoclonal Antibody (RM114), Biotin
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA527911 | 50 µL | 660,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function. GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling. Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis and as part of the cellular phenotype of age-related
Category | Antibody |
Supplier | ThermoFisher |
Application | ChIP, ICC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | A peptide corresponding to the C-terminus of GAPDH |
Host | Rb |
Clone Number | [RM114] |
Genebank | GAPDH |
Isotype | IgG |
Crossreactivity | Multi, Hu, Ms, Rt |
Clonality | Recombi |
Format | Liquid; PBS; , with 1% BSA, 50% glycerol and 0.09% sodium azide |
Concentration | 0.5 mg/mL |
Working Dilution | Immunocytochemistry (1:200), Immunohistochemistry (1:200), ChIP Assay (1:200), Immunoprecipitatio... |
Purity | Protein A |
Conjugation | Biotin |
Storage Conditions | -20°C |
Disclaimer | Alternative CatNo: MA5-27911 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |