Phospho-Stat1 (Ser727) Recombinant Rabbit Monoclonal Antibody (Stat1S727-C6), FITC
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA528057 | 100 Tests | 429,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors. STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6. STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2. STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transc
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser727 of human phospho Stat1. |
Host | Rb |
Clone Number | [Stat1S727-C6] |
Genebank | STAT1 |
Isotype | IgG,k |
Crossreactivity | Hu, Ms |
Clonality | Recombi |
Format | Liquid; PBS; pH 7.4, with 0.2% BSA and 0.09% sodium azide |
Working Dilution | Flow Cytometry (5 µL/1x10^6 cells) |
Purity | Protein A/G |
Conjugation | FITC |
Storage Conditions | 4° C, store in dark |
Disclaimer | Alternative CatNo: MA5-28057 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |