CD79a Monoclonal Antibody (HM57), FITC


Catalog Number Pack Size List Price* Quantity
MA528540 100 Tests 231,00 Add

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Product Description

The antibody HM57 interacts with CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms. Recommended dilution is for 100 µL of whole blood or 1x10^6 cells in suspension. CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.

Category Antibody
Supplier ThermoFisher
Application FC
Regulatory Status RUO
Immunogen Synthetic peptide corresponding to amino acids 202-216 human CD79a
Host Ms
Clone Number [HM57]
Genebank CD79A
Isotype IgG1
Crossreactivity Bo, Ck, Ho, Gp, Hu, Marsupial, Ms, Pg, Rb, Rt, Rodent
Clonality Mab
Format liquid; PBS; pH 7.4, with 0.2% BSA and 15mM sodium azide
Working Dilution Flow Cytometry (4 µL/1x10^6 cells)
Purity Size-exclusion chromatography
Conjugation FITC
Storage Conditions 4° C, store in dark, DO NOT FREEZE!
Disclaimer Alternative CatNo: MA5-28540
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF