STRO-1 Monoclonal Antibody (STRO-1), PE
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA528636 | 100 µg | 289,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The mouse monoclonal antibody STRO-1 recognizes the cell surface antigen STRO-1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors. STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors, but does not react with committed progenitor cells (colony-forming unit granulocyte-macrophage (CFU-GM), erythroid bursts (BFU-E), and mixed colonies (CFU-Mix). From bone marrow cells, the frequency of fibroblast colony forming cells (CFU-F) is enriched approximately 100-fold in the STRO-1-positive/Glycophorin A-negative population than in the STRO-1-positive/Glycophorin A-positive population. When plated under long-term BM culture conditions, STRO-1-positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, and fibroblastic elements. A STRO-1-positive enriched subset of marrow cells is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts and chond
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | Human CD34 positive bone marrow cells |
Host | Ms |
Clone Number | [STRO-1] |
Isotype | IgM,l |
Crossreactivity | Hu, Rb, Rt |
Clonality | Mab |
Format | liquid; TBS; pH 8, with 0.2% BSA and 15mM sodium azide |
Concentration | 0.1 mg/mL |
Working Dilution | Flow Cytometry (1-5 µg/mL) |
Purity | Size-exclusion chromatography |
Conjugation | PE |
Storage Conditions | 4° C, store in dark, DO NOT FREEZE! |
Disclaimer | Alternative CatNo: MA5-28636 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |