NCoR2 Monoclonal Antibody (1212)


Catalog Number Pack Size List Price* Quantity
MA531591 100 µL 684,00 Add

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Product Description

Keep as concentrated solution. Positive Control: HBL100. Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.

Category Antibody
Supplier ThermoFisher
Application ChIP, ICC, IHC, IP, WB
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen A synthetic peptide from the human SMRT protein corresponding to amino acids 994-1005 (ASASDPHREKTQ) coupled to KLH.
Host Ms
Clone Number [1212]
Genebank NCOR2
Isotype IgG1
Crossreactivity Hu, Primate
Clonality Mab
Format Liquid; PBS; pH 7.4, with no preservative
Concentration 1 mg/mL
Working Dilution ChIP Assay (3 µg/ 1x10^6 cells), Immunoprecipitation (Assay-dependent), Immunocytochemistry (Assa...
Purity Protein G
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: MA5-31591
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Ambient
Material Safety Data Sheet Download PDF