beta Tubulin Recombinant Rabbit Monoclonal Antibody (JF41-50), HRP
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA532541 | 100 µL | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Beta-III tubulin is primarily expressed in neurons and may be involved in neurogenesis, axon guidance and maintenance. Mutations in the beta tubulin gene are the cause of congenital fibrosis of the extraocular muscles type 3. Beta-III tubulin was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues. Glutamate residues at the C-terminus of beta III tubulin can be glutamylated. The precise function of such modifications is unclear. Tubulin is phosphorylated on Ser-172 by CDK1 during cell cycle progression. Ser-172 phosphorylation inhibits tubulin incorporation i
Category | Antibody |
Supplier | ThermoFisher |
Application | WB |
Regulatory Status | RUO |
Immunogen | Synthetic peptide within Human beta Tubulin aa 398-431 |
Host | Rb |
Clone Number | [JF41-50] |
Genebank | TUBB |
Isotype | IgG |
Crossreactivity | Hu, Ms, Rt |
Clonality | Recombi |
Format | Liquid; TBS; pH 7.4, with 0.05% BSA, 40% Glycerol and no preservative |
Concentration | 1 mg/mL |
Working Dilution | Western Blot (1:500-1:2,000) |
Purity | Protein A |
Conjugation | HRP |
Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Disclaimer | Alternative CatNo: MA5-32541 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |