ATF2 Recombinant Rabbit Monoclonal Antibody (3D12)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA533115 | 100 µL | 616,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, ICC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A synthesized peptide derived from human ATF2 |
| Host | Rb |
| Clone Number | [3D12] |
| Genebank | ATF2 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Recombi |
| Format | Liquid; PBS; pH 7.4, with 150mM NaCl, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.61 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (1:50-1:200), Western Blot (1:500-1:5,000), ELISA (Assay-Dependen... |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-33115 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
