MCM7 Recombinant Rabbit Monoclonal Antibody (3U9N7)


Catalog Number Pack Size List Price* Quantity
MA535097 100 μL 562,00 Add

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Product Description

MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Altern

Category Antibody
Supplier ThermoFisher
Application ICC, IHC, IP, WB
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen A synthetic peptide corresponding to amino acids 600-700 of human MCM7.
Host Rb
Clone Number [ARC0573]
Genebank MCM7
Isotype IgG
Crossreactivity Hu, Rt
Clonality Recombi
Format Liquid; PBS; pH 7.3, with 0.05% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.38 mg/mL
Working Dilution Immunoprecipitation (1:50-1:200), Immunocytochemistry (1:50-1:200), Immunohistochemistry (1:50-1:...
Purity Affinity Chromatography
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: MA5-35097
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Ambient
Material Safety Data Sheet Download PDF