MCM7 Recombinant Rabbit Monoclonal Antibody (3U9N7)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA535097 | 100 μL | 562,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Altern
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A synthetic peptide corresponding to amino acids 600-700 of human MCM7. |
| Host | Rb |
| Clone Number | [ARC0573] |
| Genebank | MCM7 |
| Isotype | IgG |
| Crossreactivity | Hu, Rt |
| Clonality | Recombi |
| Format | Liquid; PBS; pH 7.3, with 0.05% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.38 mg/mL |
| Working Dilution | Immunoprecipitation (1:50-1:200), Immunocytochemistry (1:50-1:200), Immunohistochemistry (1:50-1:... |
| Purity | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-35097 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |