SP1 Recombinant Rabbit Monoclonal Antibody (5I3A8)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA535331 | 100 μL | 564,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A synthetic peptide corresponding to amino acids 500-600 of human SP1. |
| Host | Rb |
| Clone Number | [ARC0128] |
| Genebank | SP1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Recombi |
| Format | Liquid; PBS; pH 7.3, with 0.05% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1.55 mg/mL |
| Working Dilution | Immunocytochemistry (1:50-1:200), Immunohistochemistry (1:50-1:200), Western Blot (1:500-1:2,000)... |
| Purity | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-35331 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
