IL17RA Recombinant Rabbit Monoclonal Antibody (R004)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA535998 | 200 µg | 518,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, N |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant Human IL-17R/IL-17RA/CD217 Protein |
| Host | Rb |
| Clone Number | [R004] |
| Genebank | IL17RA |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Recombi |
| Format | Liquid; arginine, histidine; , with 0.02% Tween 80 and no preservative |
| Working Dilution | Flow Cytometry (0.5-2 µg/test), Neutralization (Assay-dependent) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-35998 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
