Phospho-Akt1 (Ser473) Recombinant Rabbit Monoclonal Antibody (AktS473-C7), FITC
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA536905 | 100 Tests | 500,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC |
| Regulatory Status | RUO |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser473 of human phospho Akt1. |
| Host | Rb |
| Clone Number | [AktS473-C7] |
| Genebank | AKT1 |
| Isotype | IgG,k |
| Crossreactivity | Hu, Ms |
| Clonality | Recombi |
| Format | Liquid; PBS; , with 0.20% BSA and 0.09% sodium azide |
| Working Dilution | Flow Cytometry (5 µL/1x10^6 cells) |
| Purity | Protein A/G |
| Conjugation | FITC |
| Storage Conditions | 4° C, store in dark |
| Disclaimer | Alternative CatNo: MA5-36905 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
