Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5), FITC
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA536937 | 100 Tests | 502,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC |
| Regulatory Status | RUO |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1. |
| Host | Rb |
| Clone Number | [4EB1T37T46-A5] |
| Genebank | EIF4EBP1 |
| Isotype | IgG,k |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Recombi |
| Format | Liquid; PBS; , with 0.20% BSA and 0.09% sodium azide |
| Working Dilution | Flow Cytometry (5 µL/1x10^6 cells) |
| Purity | Protein A/G |
| Conjugation | FITC |
| Storage Conditions | 4° C, store in dark |
| Disclaimer | Alternative CatNo: MA5-36937 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
