Phospho-Histone H3 (Ser10) Recombinant Rabbit Monoclonal Antibody (HisH3S10-4B6), FITC
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA536951 | 100 Tests | 502,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC |
| Regulatory Status | RUO |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser10 of human phospho histone H3. |
| Host | Rb |
| Clone Number | [HisH3S10-4B6] |
| Genebank | H3C1 |
| Isotype | IgG,k |
| Crossreactivity | Hu |
| Clonality | Recombi |
| Format | Liquid; PBS; , with 0.20% BSA and 0.09% sodium azide |
| Working Dilution | Flow Cytometry (5 µL/1x10^6 cells) |
| Purity | Protein A/G |
| Conjugation | FITC |
| Storage Conditions | 4° C, store in dark |
| Disclaimer | Alternative CatNo: MA5-36951 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
