5-Methylcytosine Monoclonal Antibody (33D3)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA538432 | 100 µg | 552,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | DB, ICC, IP |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | 5-Methylcytosine nucleotide |
| Host | Ms |
| Clone Number | [33D3] |
| Isotype | IgG1 |
| Crossreactivity | Chemical |
| Clonality | Mab |
| Format | Liquid; PBS; , with 0.05% sodium azide |
| Concentration | 2.6 mg/mL |
| Working Dilution | Dot Blot (Assay-dependent), Immunocytochemistry (1:500), Methylated DNA Immunoprecipitation (0.5-... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-38432 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
