H3K27cr Recombinant Rabbit Monoclonal Antibody (RM401)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA538669 | 100 µL | 558,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | DB, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A crotonyl-peptide corresponding to Crotonyl-Histone H3 (Lys27) |
| Host | Rb |
| Clone Number | [RM401] |
| Genebank | H3C1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Recombi |
| Format | Liquid; PBS; , with 1% BSA, 50% glycerol and 0.09% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Western Blot (0.5-2 µg/mL), Dot Blot (0.5-2 µg/mL) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-38669 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
