Brontictuzumab Recombinant Human Monoclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA542025 | 100 µg | 487,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Endotoxin level < 0.01EU/µg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt. Brontictuzumab is a biosimilar that targets NOTCH1. The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, WB |
Regulatory Status | RUO |
Immunogen | Human NOTCH1 |
Host | Hu |
Isotype | IgG2,l |
Crossreactivity | Chemical |
Clonality | Recombi |
Format | Liquid; PBS; pH 7.4, with no preservative |
Concentration | 1.0 mg/mL |
Working Dilution | Western Blot (Assay-dependent), ELISA (Assay-dependent) |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA5-42025 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |