Narsoplimab Recombinant Human Monoclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA542178 | 100 µg | 487,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Endotoxin level < 0.01EU/µg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt. Narsoplimab is a human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), the effector enzyme of the lectin pathway of the complement system. The lectin pathway is one of the principal pathways of complement and is activated primarily by tissue damage and microbial infection. Importantly, inhibition of MASP-2 does not appear to interfere with the classical complement pathway, a critical component of the acquired immune response to infection. This novel, proprietary pharmaceutical is designed to prevent complement-mediated inflammation and endothelial damage while leaving intact the respective functions of the other pathways of innate immunity.
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, WB |
Regulatory Status | RUO |
Immunogen | Human MASP2 |
Host | Hu |
Isotype | IgG4,l |
Crossreactivity | Chemical |
Clonality | Recombi |
Format | Liquid; PBS; pH 7.5, with no preservative |
Concentration | 1.1 mg/mL |
Working Dilution | ELISA (Assay-dependent), Western Blot (Assay-dependent) |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: MA5-42178 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |